Endocrine Abstracts

We present a case of 70 year-old-man, who was referred to the endocrine clinic with incidentally detected 26 mm lesion arising from the left adrenal gland suspicious of pheochromocytoma. This was detected during investigations for asymptomatic microscopic haematuria. He did not describe the typical symptoms of pheochromocytoma (episodic headaches, sweating, tachycardia), but interestingly 4–5 months previously was diagnosed with an acute onset of psychosis with paranoid d...

Background: Pituitary abscess is a rare entity which is often not suspected in pituitary lesions differential diagnoses; arising de novo or as a consequence of sinus infection, meningitis, or haematogenous spread. The diagnosis is challenging and mostly made during surgery.Case Report: A 54-year-old male patient presented with 3 days of severe headaches, vomiting, and left eyelid drooping. He was afebrile, BP 90/61mmHg, and had a left third nerve palsy w...

Background: Non-functioning pituitary adenomas (NFPAs) are the most common pituitary macroadenomas with a prevalence of 7-22 per 100,000 population. As they are non-secretory, they tend to present late with visual disturbances, headaches or hormonal deficiencies. Surgery is the main treatment for NFPAs, particularly endoscopic transsphenoidal surgery which can be associated with surgical and endocrine complications.Aims: To compare pre- and post-operativ...

Post-pituitary surgery hyponatraemia (HN, sodium <135 mmol/l) is relatively common and may result in prolonged hospitalisation. Herein we report a retrospective analysis of our experience in a tertiary institute. We conducted a retrospective case note review of 318 patients (M 54%, F 46%, mean age 58 years) 65.7% non-functioning adenoma (NFA), 10% somatotropinoma, 5% prolactinoma, 11% corticotropinoma (half were clinically silent), 8% craniopharyngioma, an...

Introduction: We present a series of 10 cases of GD presenting with seemingly unrelated symptoms with limited features of thyrotoxicosis, where control of thyroid function tests (TFTs) led to complete normalisation of presenting symptoms. In all cases patients were shown to have Graves disease with thyroid antibodies.Case series review: 1. 82F with symptomatic hypercalcaemia and thymic hyperplasia on CT. Calcium normalised with standard therapy and remai...

Hyperthyroidism is common and in iodine-sufficient parts of the world the prevalence of overt hyperthyroidism is estimated to be 0.2% to 1.3%. The treatment options include antithyroid medication (ATD), thyroid surgery, or Radioactive iodine (RAI). The latter is increasingly used as a first line definitive treatment for hyperthyroidism. We reviewed the outcomes of patients who received RAI at our tertiary nuclear medicine department over a 4-year period (May 2015 to Dec 2019) ...

Background: Craniopharyngioma (CP) is a rare sellar or suprasellar epithelial tumour with a prevalence of approximately 2 per million and it occurs either in childhood between the ages of 5 and 14 years or in adulthood between the ages of 50 and 74 years. Histologically, CPs are divided into adamantinomatous, more prevalent in children, and papillary, more prevalent in adults. They are usually benign, but rare cases of malignant CPs have been reported. Clinical presentation is...